Download scientific diagram | – Cnidoscolus quercifolius plant. from publication: Análise Química e Bromatológica da Forragem da Faveleira (Cnidoscolus. PDF | Objective: To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential. The Cnidoscolus quercifolius (Pohl) popularly known as “favela” or “faveleira” is a forager that is part of the native species from the caatinga.

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In a test of cnidoscouls against Artemia cnldoscolusconducted by Fabri et al. Subscribe to Table of Contents Alerts. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The semiarid region of the Brazilian Northeast is known for hosting a number of native species that are under systematic exploitation in recent years, without any sustainable management, which ultimately causes the extinction of some species, thus unleashing a rural exodus.

The methodology began with the collection and herborization of the plant material, to obtain the chemical compounds, preliminary phytochemical analysis, and extraction of the constituents of the active extracts. Due to this increased interest, research on plants of medicinal importance is growing phenomenally at the international level. View at Google Scholar F. The importance of medicinal plants in solving the health problems of the world is gaining more and more attention.

Antimicrobial assays against bacterial strains and fungi tested, using commercial drugs Chloramphenicol, Streptomycin, and Thiabendazole as a positive control, showed no growth of microorganisms. The high-performance liquid chromatography with diode-array quercifoliuus and 1 H and 13 C nuclear magnetic resonance spectroscopy of the extract were used to distinguish the existence of possible functional groups in the root bark extract.

The extract from the bark quercifollius C. To receive news and publication updates for Evidence-Based Complementary and Alternative Medicine, enter your email address in the box below.

All the methanolic extracts of the faveleira presented anticholinesterase activity. In the bark of C.

Evidence-Based Complementary and Alternative Medicine

View at Google Scholar M. It is widely used as fodder for cattle and small ruminants, mainly in the dry periods.


Therefore, the root bark extract of Cnidoscolus quercifolius has a possibility of use for anticarcinogenic therapies. Table 2 shows the results of cbidoscolus activity of methanolic extracts of C. Result of inhibition of the acetylcholinesterase enzyme from methanolic extracts of C. De Almeida Alves, A. As far as we know, there are no data in the literature showing the antioxidant activity of samples of C. Souza [ 55 ] describes that the absence of toxicity can be an advantage for the possibility of using isolated substances in developing herbal medicines for use in humans.

Related articles Cnidoscolus quercifolius Pohl. The United States and Germany rank among the biggest consumers of natural products from Brazil.

Cnidoscolus quercifolius – Wikipedia

In the evaluation of toxicity of methanolic extracts of C. Moreover, a growing number of people are seeking traditional medicine for their primary health care. TLC evaluated inhibition of acetylcholinesterase enzyme AChEin accordance with the methodology described by Ellman et al. Most studies on the faveleira are targeted at its use in the agricultural and livestock fields, and very few studies of the querxifolius focus on the area of chemistry of natural products and biological activity.

Preliminary Phytochemical Analysis The extracts were subjected to phytochemical screening, following the protocols described by Mattos [ 16 ]. Thus, the therapeutic potential of native plants must be scientifically demonstrated, so that it can be exploited in a rational and orderly manner [ 1112 ]. Disks containing Streptomycin 1. Table of Contents Alerts. In Qjercifolius, the first Europeans who settled in the land ran across a large quantity of medicinal plants used by the indigenous populations who lived here.

For this reason, the present study focuses on the assessment of the therapeutic potential of this plant, by investigating its possible antioxidant, antimicrobial, and inhibitory activity of the acetylcholinesterase enzyme AChEas well as the toxicity of the qjercifolius extracts from three parts of Cnidoscolus quercifolius Pohl.

View at Google Uqercifolius U. Ahmad and Beg [ 44 ] believe that the antimicrobial effect of vegetal extracts is largely due to the presence of flavonoids in their cnifoscolus, thus corroborating the results found for the C. Materials and Methods 2.

Several studies have shown the use of Artemia salina to evaluate the toxicity of extracts, of isolated and purified substances of medicinal plants [ 3151 — 54 ], thus decreasing the use of animals for experimentation.


It was the start of a series of cultural intermixes that blended the knowledge brought in by the colonizers, the slaves, and the natives.

Cnidoscolus quercifolius

Tests were performed for the detection of phenols and tannins, anthocyanins and anthocyanidins, flavones, flavonols, xanthones, flavanones, chalcones and aurones, leucoanthocyanidins, catechins, steroids and triterpenoids, and saponins.

These bioactive molecules exhibit a variety of biological effects, such as antithrombotic, anti-inflammatory, and anticancer effects, as a result of their antioxidant properties [ 41 ].

View at Google Scholar R. To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential against several tumor strains. Corroborating this, Kutchan [ 33 ] reports that the secondary metabolites have a direct relationship with plants and the environment in which they live; therefore, their synthesis is often affected by environmental conditions.

None, Conflict of Interest: The analysis of nuclear magnetic spectra of the active chloroform fraction revealed the presence of absorptions bands correspondent to a mixture of favelines such as neofavelanone, deoxofaveline or methyl-faveline, which structures were confirmed by ultraviolet spectra upon high-performance liquid chromatography with diode-array detection analysis.

It stands out for its extraordinary drought resistance and medicinal properties. In the agar diffusion method, the extracts showed activity against strains of Staphylococcus and E. These are samples of crude extracts and may therefore be considered a meaningful result, suggesting the need to isolate the compounds responsible for sequestering the free radicals, thus achieving an index even closer to the default.

With the aid of a light source, the hatched larvae were attracted to the lightened vessel part and were collected with a Pasteur pipette and then transferred to a beaker with saline water. For Holetz et al. Brine shrimp lethality test of the methanolic extracts from C.